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Index > Protein center > Arhgap21(Gene name) > Mouse
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  • Arhgap21 (Gene name),
  • Rho GTPase-activating protein 21 (Protein name ),  RHG21_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Arhgap21(Arhgap10;Kiaa1424);
    Protein name:
    Rho GTPase-activating protein 21;
    Alternative:
    Rho-type GTPase-activating protein 21;Rho GTPase-activating protein 10;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with CTNNA1 (By similarity). Interacts with GTP-bound ARF1 and probably ARF6.
    Function:
    Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions.
    Subcellular Location:
    Golgi apparatus membrane Peripheral membrane protein Cell junction Cytoplasmic vesicle membrane Peripheral membrane protein Cytoplasm cytoskeleton Localization to the Golgi is dependent on interaction with GTP-bound ARF1.
    Protein Attributes:
    Sequence length:
    1944
    Sequence:
    50:
    MATHWTGLPE | EDGDKLKACG | AASACEVSKN | KDGKDQGEPV | SPSEDEPFSW | 
    100:
    PGPKTVMLKR | TSQGFGFTLR | HFIVYPPESA | IQFSYKDEEN | GNRGGKQRNR | 
    150:
    LEPMDTIFVK | QVKEGGPAFE | AGLCTGDRII | KVNGESVIGK | TYSQVIALIQ | 
    200:
    NSDTTLELSV | MPKDEDILQV | AYSQDAYLKG | NEAYSGNARN | IPEPPPVCYP | 
    250:
    WLPSTPSATA | QPVETCPPDS | LPNKQQTSAP | VLTQPGRAYR | MEIQVPPSPT | 
    300:
    DVAKSNTAVC | VCNESVRTVI | VPSEKVVDLL | ANRNNPSGPS | HRTEEVRYGV | 
    350:
    NEQASTKAAS | RTTSPASVPT | AHLIHQTTGS | RSLEPSGILL | KSGNYSGHSE | 
    400:
    GISSSRSQAV | DSPPVSVNHY | SANSHQHIDW | KNYKTYKEYI | DNRRLHIGCR | 
    450:
    TIQERLDSLR | AASQSAADYN | QVVPTRTTLQ | VRRRSTSHDR | VPQSVQIRQR | 
    500:
    SVSQERLEDS | VLMKYCPRSA | SQGALTSPPV | SFNNHRTRSW | DYIEGQTEAT | 
    550:
    ATVNSESQIP | DSNGERKQTY | KWSGFTEQDD | RRGIHERPRQ | QEMHKPFRGS | 
    600:
    NLTVAPVVNS | DNRRLVGRGV | GPVSQFKKIP | PDLRPPHSNR | NFPTTTGVSL | 
    650:
    QRGIAQDRSP | LVKVRSNSLK | VPPPPVSKPS | FSQHSLASMK | DQRPVNHLHQ | 
    700:
    HSVLSQQTQF | RSESTFEHQL | ETEVSSCLPG | TSAKTSPQLS | ENLGTSDLEL | 
    750:
    PAIPRNGDIN | LQEAEIQQPD | VLDNKESVIL | REKPQSGRQT | PQPLRHQSYI | 
    800:
    LAVNDQETGS | DTTCWLPNDA | RREVHIKRME | ERKASSTSPP | GDSLASIPFI | 
    850:
    DEPTSPSIDH | EIAHIPASAV | ISASTAHVPS | IATVPPSLTT | SAPLIRRQLS | 
    900:
    HDQESVGPPS | LDGQHSSKTE | RSKSYDEGLD | DYREDAKLSF | KHVSSLKGIK | 
    950:
    ITDSQKSSED | SGSRKGSSSE | VFSDAAREGW | LQFRPLVTDK | GKRVGGSIRP | 
    1000:
    WKQMYVVLRG | HSLYLYKDRR | EQTTPSEEEQ | PISVNACLID | ISYSETKRRN | 
    1050:
    VFRLTTSDCE | CLFQAEDRDD | MLSWIKTIQE | SSNLNEEDTG | VTNRDLISRR | 
    1100:
    IKEYNSLLSK | TEQLPKTPRQ | SLSIRQTLLG | AKSEPKTQSP | HSPKEESERK | 
    1150:
    LLSKDDTSPP | KDKGTWRRGI | PSIVRKTFEK | KPAATGTFGV | RLDDCPPAHT | 
    1200:
    NRYIPLIVDI | CCKLVEERGL | EYTGIYRVPG | NNAAISSMQE | ELNKGMADID | 
    1250:
    IQDDKWRDLN | VISSLLKSFF | RKLPEPLFTN | DKYADFIEAN | RKEDPLDRLR | 
    1300:
    TLKRLIHDLP | EHHFETLKFL | SAHLKTVAEN | SEKNKMEPRN | LAIVFGPTLV | 
    1350:
    RTSEDNMTHM | VTHMPDQYKI | VETLIQHHDW | FFTEEGAEEP | LTAVQEENTV | 
    1400:
    DSQPVPNIDH | LLTNIGRTGV | LPGDVSDSAT | SDSAKSKGSW | GSGKDQYSRE | 
    1450:
    LLVSSIFAAA | SRKRKKPKEK | AQPSSSEDEL | DSVFFKKENT | EQSHSEIKEE | 
    1500:
    SKRESETSGS | KQRVVVAKES | NTKKDSGTTK | EEKKIPWEEP | PPPHSSKRNR | 
    1550:
    SPTLSCRLAM | LKEGPRSLLT | QKPHCEETGS | DSGTLLSTSS | QASLLRSSTK | 
    1600:
    KSTSPETKHS | EFLSIAGTTT | SDYSTTSSTT | YLTSLDSSRL | SPEVQSVAES | 
    1650:
    KGDEADDERS | ELVSEGRPVE | TDSESEFPVF | PTTLTSDRLF | RGKFQEVARV | 
    1700:
    SRRNSEGSEA | SCTEGSLTPS | LDSRRQQFSS | HRLIECDTLS | RKKSARFKSD | 
    1750:
    SGSPGDTRTE | KETPALAKMF | DVMKKGKSTG | SLLTPSRSES | EKQEATWKTK | 
    1800:
    IADRLKLRPR | APADDMFGVG | NQKPTAETAK | RKNIKRRHTL | GGHRDATEIS | 
    1850:
    VLSFWKAHEQ | SADKESELSA | VNRLKPKCSA | QDLSISDWLA | RERVRTSASD | 
    1900:
    LSRGEGLEPQ | AESPSVLGTP | ISTHSPPSQQ | PEARVAATST | LASTSQSPLF | 
    1944:
    TPPQSPDQIN | RESFQNMSQN | ASSTANIHPH | KQSESPDTKA | ETPP
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    UniGene:
    SMR:
    Pfam:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse Rho GTPase-activating protein 21
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    E1568h
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    ELISA Kit for Mouse Rho GTPase-activating protein 21
    Cat.:
    E1568m
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    Packing:
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    CLIA Kit for Mouse Rho GTPase-activating protein 21
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    U1568m
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    Packing:
    96T
    CLIA Kit for Mouse Rho GTPase-activating protein 21
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    U1568h
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    MSDS:
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    Packing:
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    Polyclonal Antibody for Mouse Rho GTPase-activating protein 21
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    P1568Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse Rho GTPase-activating protein 21
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    P1568Rb-h
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse Rho GTPase-activating protein 21
    Monoclonal Antibody for Mouse Rho GTPase-activating protein 21
    Protein for Mouse Rho GTPase-activating protein 21
    Protein for Mouse Rho GTPase-activating protein 21

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: C57BL/6J.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Brain.
      tissue: Head.
    3. 3.
      "Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
      Okazaki N. , Kikuno R. , Ohara R. , Inamoto S. , Aizawa H. , Yuasa S. , Nakajima D. , Nagase T. , Ohara O. , Koga H.
      DNA Res.10:35-48(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 683-1944
      tissue: Brain.
    4. 4.
      Lubec G. , Sunyer B. , Chen W.-Q.
      Submitted (2009-01) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1697-1708;IDENTIFICATION BY MASS SPECTROMETRY
      strain: OF1.
      tissue: Hippocampus.
    5. 5.
      "Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
      Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
      Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1092;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Brain.
    6. 6.
      "Structural basis for ARF1-mediated recruitment of ARHGAP21 to Golgi membranes."
      Menetrey J. , Perderiset M. , Cicolari J. , Dubois T. , Elkhatib N. , El Khadali F. , Franco M. , Chavrier P. , Houdusse A.
      EMBO J.26:1953-1962(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ARF1
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    8. 8.
      "The phagosomal proteome in interferon-gamma-activated macrophages."
      Trost M. , English L. , Lemieux S. , Courcelles M. , Desjardins M. , Thibault P.
      Immunity30:143-154(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-917;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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