Gene name:
Arhgap21 (Arhgap10;Kiaa1424) ;
Protein name:
Rho GTPase-activating protein 21 ;
Alternative:
Rho-type GTPase-activating protein 21 ;Rho GTPase-activating protein 10 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with CTNNA1 (By similarity). Interacts with GTP-bound ARF1 and probably ARF6.
Function:
Functions as a GTPase-activating protein (GAP) for RHOA and CDC42. Downstream partner of ARF1 which may control Golgi apparatus structure and function. Also required for CTNNA1 recruitment to adherens junctions.
Subcellular Location:
Golgi apparatus membrane
Peripheral membrane protein
Cell junction
Cytoplasmic vesicle membrane
Peripheral membrane protein
Cytoplasm
cytoskeleton
Localization to the Golgi is dependent on interaction with GTP-bound ARF1.
Protein Attributes:
50:
MATHWTGLPE | EDGDKLKACG | AASACEVSKN | KDGKDQGEPV | SPSEDEPFSW |
100:
PGPKTVMLKR | TSQGFGFTLR | HFIVYPPESA | IQFSYKDEEN | GNRGGKQRNR |
150:
LEPMDTIFVK | QVKEGGPAFE | AGLCTGDRII | KVNGESVIGK | TYSQVIALIQ |
200:
NSDTTLELSV | MPKDEDILQV | AYSQDAYLKG | NEAYSGNARN | IPEPPPVCYP |
250:
WLPSTPSATA | QPVETCPPDS | LPNKQQTSAP | VLTQPGRAYR | MEIQVPPSPT |
300:
DVAKSNTAVC | VCNESVRTVI | VPSEKVVDLL | ANRNNPSGPS | HRTEEVRYGV |
350:
NEQASTKAAS | RTTSPASVPT | AHLIHQTTGS | RSLEPSGILL | KSGNYSGHSE |
400:
GISSSRSQAV | DSPPVSVNHY | SANSHQHIDW | KNYKTYKEYI | DNRRLHIGCR |
450:
TIQERLDSLR | AASQSAADYN | QVVPTRTTLQ | VRRRSTSHDR | VPQSVQIRQR |
500:
SVSQERLEDS | VLMKYCPRSA | SQGALTSPPV | SFNNHRTRSW | DYIEGQTEAT |
550:
ATVNSESQIP | DSNGERKQTY | KWSGFTEQDD | RRGIHERPRQ | QEMHKPFRGS |
600:
NLTVAPVVNS | DNRRLVGRGV | GPVSQFKKIP | PDLRPPHSNR | NFPTTTGVSL |
650:
QRGIAQDRSP | LVKVRSNSLK | VPPPPVSKPS | FSQHSLASMK | DQRPVNHLHQ |
700:
HSVLSQQTQF | RSESTFEHQL | ETEVSSCLPG | TSAKTSPQLS | ENLGTSDLEL |
750:
PAIPRNGDIN | LQEAEIQQPD | VLDNKESVIL | REKPQSGRQT | PQPLRHQSYI |
800:
LAVNDQETGS | DTTCWLPNDA | RREVHIKRME | ERKASSTSPP | GDSLASIPFI |
850:
DEPTSPSIDH | EIAHIPASAV | ISASTAHVPS | IATVPPSLTT | SAPLIRRQLS |
900:
HDQESVGPPS | LDGQHSSKTE | RSKSYDEGLD | DYREDAKLSF | KHVSSLKGIK |
950:
ITDSQKSSED | SGSRKGSSSE | VFSDAAREGW | LQFRPLVTDK | GKRVGGSIRP |
1000:
WKQMYVVLRG | HSLYLYKDRR | EQTTPSEEEQ | PISVNACLID | ISYSETKRRN |
1050:
VFRLTTSDCE | CLFQAEDRDD | MLSWIKTIQE | SSNLNEEDTG | VTNRDLISRR |
1100:
IKEYNSLLSK | TEQLPKTPRQ | SLSIRQTLLG | AKSEPKTQSP | HSPKEESERK |
1150:
LLSKDDTSPP | KDKGTWRRGI | PSIVRKTFEK | KPAATGTFGV | RLDDCPPAHT |
1200:
NRYIPLIVDI | CCKLVEERGL | EYTGIYRVPG | NNAAISSMQE | ELNKGMADID |
1250:
IQDDKWRDLN | VISSLLKSFF | RKLPEPLFTN | DKYADFIEAN | RKEDPLDRLR |
1300:
TLKRLIHDLP | EHHFETLKFL | SAHLKTVAEN | SEKNKMEPRN | LAIVFGPTLV |
1350:
RTSEDNMTHM | VTHMPDQYKI | VETLIQHHDW | FFTEEGAEEP | LTAVQEENTV |
1400:
DSQPVPNIDH | LLTNIGRTGV | LPGDVSDSAT | SDSAKSKGSW | GSGKDQYSRE |
1450:
LLVSSIFAAA | SRKRKKPKEK | AQPSSSEDEL | DSVFFKKENT | EQSHSEIKEE |
1500:
SKRESETSGS | KQRVVVAKES | NTKKDSGTTK | EEKKIPWEEP | PPPHSSKRNR |
1550:
SPTLSCRLAM | LKEGPRSLLT | QKPHCEETGS | DSGTLLSTSS | QASLLRSSTK |
1600:
KSTSPETKHS | EFLSIAGTTT | SDYSTTSSTT | YLTSLDSSRL | SPEVQSVAES |
1650:
KGDEADDERS | ELVSEGRPVE | TDSESEFPVF | PTTLTSDRLF | RGKFQEVARV |
1700:
SRRNSEGSEA | SCTEGSLTPS | LDSRRQQFSS | HRLIECDTLS | RKKSARFKSD |
1750:
SGSPGDTRTE | KETPALAKMF | DVMKKGKSTG | SLLTPSRSES | EKQEATWKTK |
1800:
IADRLKLRPR | APADDMFGVG | NQKPTAETAK | RKNIKRRHTL | GGHRDATEIS |
1850:
VLSFWKAHEQ | SADKESELSA | VNRLKPKCSA | QDLSISDWLA | RERVRTSASD |
1900:
LSRGEGLEPQ | AESPSVLGTP | ISTHSPPSQQ | PEARVAATST | LASTSQSPLF |
1944:
TPPQSPDQIN | RESFQNMSQN | ASSTANIHPH | KQSESPDTKA | ETPP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse Rho GTPase-activating protein 21
ELISA Kit for Mouse Rho GTPase-activating protein 21
CLIA Kit for Mouse Rho GTPase-activating protein 21
CLIA Kit for Mouse Rho GTPase-activating protein 21
Polyclonal Antibody for Mouse Rho GTPase-activating protein 21
Polyclonal Antibody for Mouse Rho GTPase-activating protein 21
Monoclonal Antibody for Mouse Rho GTPase-activating protein 21
Monoclonal Antibody for Mouse Rho GTPase-activating protein 21
Protein for Mouse Rho GTPase-activating protein 21
Protein for Mouse Rho GTPase-activating protein 21
R&D Technical Data
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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References
1.
"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M.
,
Goodstadt L.
,
Hillier L.W.
,
Zody M.C.
,
Goldstein S.
,
She X.
,
Bult C.J.
,
Agarwala R.
,
Cherry J.L.
,
DiCuccio M.
,
Hlavina W.
,
Kapustin Y.
,
Meric P.
,
Maglott D.
,
Birtle Z.
,
Marques A.C.
,
Graves T.
,
Zhou S.
,
Teague B.
,
Potamousis K.
,
Churas C.
,
Place M.
,
Herschleb J.
,
Runnheim R.
,
Forrest D.
,
Amos-Landgraf J.
,
Schwartz D.C.
,
Cheng Z.
,
Lindblad-Toh K.
,
Eichler E.E.
,
Ponting C.P.
more...
PLoS Biol.7:E1000112-E1000112(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain :
C57BL/6J .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6 .
tissue :
Brain .
tissue :
Head .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 683-1944
tissue :
Brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PROTEIN SEQUENCE OF 1697-1708;IDENTIFICATION BY MASS SPECTROMETRY
strain :
OF1 .
tissue :
Hippocampus .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1092;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Brain .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH ARF1
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-917;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]